Radioactive 125I interstitial brachytherapy damages to intestinal tract tissue and protection research pro-gress
- VernacularTitle:125I组织间放疗与肠道组织损伤及防护
- Author:
Can MA
;
Yan GUO
- Publication Type:Journal Article
- Keywords:
Brachytherapy;
Gastrointestinal tract;
Radiation injuries;
Radiation protection
- From:
Journal of International Oncology
2008;35(6):453-455
- CountryChina
- Language:Chinese
-
Abstract:
Radioactive 125I interstitial brachytherapy is easy to cause the intestinal tract tissue damage.Its mechanism possibly correlates to the quick renewal speed of the intestinal tract tissue and a majority of ceils in M, G2 and late S phases. The tolerant dose of intestinal tract tissue is approximately 160 Gy. If the absorbed dose is higher than the tolerant one, the intestinal tract tissue will be damaged. In the clinical practice of radio-active 125I interstitial brachytherapy, through the strict plan of the TPS system before the operation, by using ul-trasound, CT, MR/and other imaging technologies in the operating process and establishing the suitable barrier protection between the seeds and intestinal tract tissue, the radioactive damage of the intestinal tract tissue my be reduced.
