The study on ocular motor function of patients with Parkinson disease at early and moderate stage
- VernacularTitle:早中期老年帕金森病患者眼球运动异常的临床研究
- Author:
Li YING
;
Zhenguo LIU
;
Wenan WANG
;
Wei CHEN
;
Jing GAN
- Publication Type:Journal Article
- Keywords:
Parkinson disease;
Eye movement;
Saceade;
Electronystagmography
- From:
Chinese Journal of Geriatrics
2008;27(7):514-517
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study ocular motor function in patients with Parkinson disease.Methods Videonystagmography(VNG)was used for testing ocular saccade and smooth pursuit eye movement(SPEM)in 14 patients with idiopathic Parkinson disease and 10 age and sex-matched control subjects to compare the latency of saccades,the accuracy of saeeades and SPEMGain between two groups. Results The latency of saceades was found to be much more increased in PD group (291.23±46.25)ms than that in healthy group(244.45±23.11)ms(P<0.05);and the accuracy of saccades was found to be decreased in PD group(87.98±6.1 6)as compared to that in healthy group (95.21±8.56)(P<0.05).PD group was found to have more decreased SPEM gain(0.81±0.12)than that in healthy group(0.90±0.1 5)(P<0.05). Conclusions The findings suggest that ocular motor function is abnormal in Parkinson disease patients.