Breast tumor size assessment:comparison of conventional ultrasound and real-time ultrasonic elastography
- VernacularTitle:超声弹性成像与常规超声的病灶测值变化对乳腺病变的诊断价值
- Author:
Qingli ZHU
;
Yuxin JIANG
;
He LIU
;
Qing ZHANG
;
Qiang SUN
;
Qing DAI
;
Weixun ZHOU
- Publication Type:Journal Article
- Keywords:
Ultrasonography,mammary;
Breast diseases;
Ultrasound elastography
- From:
Chinese Journal of Ultrasonography
2008;17(6):508-512
- CountryChina
- Language:Chinese
-
Abstract:
Objective Tumor size discrepancy in measurement between real-time ultrasonic elastography and conventional uItrasound(US) was found in some breast lesions.The study was designed to investigate the value of the feature in the diagnosis of breast cancer,and its relationship with the margin features on gray-scale US.Methods Both US and real-time elastogram using a Hitachi EUB-8500 US system were performed in 308 consecutive Datients.The margin features on US and the size measured on both methods were documented.A lesion was defined as a significant size discrepancy when a larger size measured at elastogram.Sensitivity,specificity,and overall accuracy of feature to diagnosis malignancy were determined by surgical pathology as gold standard.Results There were total 166 benign,163 malignant and 3 borderline lesions.of 99 lesions with larger measurement on elastography,there were 91 malignant lesions and 8 benign lesions.By the feature of size discrepancY,the sensitivity,specificity and accuracy was achieved 55.8%,96.9%,75.7%,respectively.The size measured on elastogram was statistically larger than that on gray scale US(t=-11.0,P＜0.05).The ratio of indistinct,angular and spiculated margin characteristics were significantly higher in breast cancers with larger size measurement than those with unchanged or decreased size measurement(P＜0.05).Conclusions The increased size-measurement at elastography is helpful to diagnosis breast cancers.And it is more likely to be present in breast cancers with indistinct,angular or spiculated margin.
