Meta analysis of transcatheter arterial chemoembolization before hepatectomy for primary hepatocellular carcinoma
- VernacularTitle:原发性肝癌肝切除术前经肝动脉化疗栓塞的META分析
- Author:
Lei YIN
;
Zeya PAN
;
Bowen WU
;
Hui LIU
;
Jin ZHANG
;
Weiping ZHOU
- Publication Type:Journal Article
- Keywords:
liver neoplasm;
hepatectomy;
transcatheter arterial chemoembolization;
meta analysis
- From:
International Journal of Surgery
2008;35(7):457-460
- CountryChina
- Language:Chinese
-
Abstract:
Objective This study was to systemically evaluate the efficacy of TACE before hepatectomy on resectable primary HCC.Methods The articles focused on preoperative TACE for resectable primary HCC,published from Jan.1,1980 to Jan.1,2008,were selected by computerized search of literatures and manual search of bibliographies.The clinical controlled trials meeting inclusion criteria were reviewed systematically by meta-analysis.The reported data were processed with the statistical techniques of meta analysis.The combinability of the studies was assessed in terms of clinical and statistical criteria.Tumor-free survival rate was calculated.And pooled estimates were computed according to a fixed or random effect model by heterogeneity.Results A total of 1288 patients were included in 8 trials.There was no difference between the two groups in the 1,3-year tumor-free survival rate.Conclusion Preoperative TACE for resectable primary hepatic carcinoma can't improve survival rate.
