Observation of therapeutic effects in arterial interventional therapy in early osteosarcoma patients
- VernacularTitle:早期骨肉瘤患者动脉介入治疗疗效观察
- Author:
Quanming WANG
;
Zhixiang MAO
;
Meng ZHANG
;
Xinsheng QI
;
Xiaoqi YANG
- Publication Type:Journal Article
- Keywords:
Osteosarcoma;
Arteries;
Embolization,therapeutic;
Surgical procedures,operafive
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(20):24-26
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical therapeutic effects in arterial interventional therapy in early osteosarcoma patients.Methods Thirty-eight early osteosarcoma patients received arterial chemoembolization therapies and performed operations.94.7% patients received limb salvage surgeries.Levels of alkaline phosphatase were tested in preoperative and postoperative phases.Results Levels of postoperativealkaline phosphatase[average(191.7±107.0)U/L]were significantly decreased compared with that before interventional therapy[average(1129.1±572.3)U/J.The survival rate in follow-up at 1,3 and 5 years Was97%,79%,50% respectively.The rate of recurrence and metastasis WAg 24%.Conclusions Arterialchemoembolization therapies in patients with early osteosarcoma could improve clinical symptoms effectively,enhance survival rate,relieve recurrence and metastasis,remain affected extremity.The clinical thempeutic effects of iodinated oil were the best among the three embolism materials.
