Recent advance in transplantation tolerance induced by apoptosis of T lymphocyte
- VernacularTitle:T淋巴细胞凋亡与移植免疫耐受的研究进展
- Author:
Xiaodong SHEN
;
Jianbin XIANG
;
Zongyou CHEN
- Publication Type:Journal Article
- Keywords:
apoptosis;
T lymphocyte;
organ transplantation;
immune tolerance
- From:
International Journal of Surgery
2008;35(7):471-474
- CountryChina
- Language:Chinese
-
Abstract:
Apoptosis is great advancement in sphere of biology,it is characteristic death form at physiological state.Rencent researchs discover that apoptosis take important role in transplantation immunity.That graft is rejected is the major obstruction in transplantation.Allogeneic transplantation rejection is because of immune response that is mediated by T lymphocyte and aimed directly at allogenic antigen.Apoptosis of activated T lymphocyte through some pathways can induce immune tolerance.Some immune suppressant produce effect just by cell apoptosis.This review mainly presents recent advance in transplantation tolerance induced by apoptosis of T lymphocyte.
