Antitumor effect of bifidobacterium
- VernacularTitle:双歧杆菌的抗肿瘤作用
- Author:
Liqiang ZHONG
- Publication Type:Journal Article
- Keywords:
Bifidobacterium;
Neoplasms;
Gene therapy
- From:
Journal of International Oncology
2008;35(6):414-417
- CountryChina
- Language:Chinese
-
Abstract:
Bifidohacterium is an inherent intestinal microflora. It is anaerobic, nonpathogenic and bad-less. Researches have demonstrated that bifidohacterium can inhibit tumor cells growth, induce tumor cells apop-tosis and stimulate the immunocytes secreting cytokines. Because it can selectively localizes and proliferates in solid tumors,it can be used as a delivery system for tumor-targeting enzyme-prodrug in geoe therapy. In vivo studies show that bifidobacterium is an ideal biologic agent which can be used to treat tumor without toxicity.
