Comparison of two treatment methods in patients of type 2 diabetes with tuberculosis
- VernacularTitle:两种方法治疗2型糖尿病合并肺结核结果比较
- Author:
Guicai ZHONG
;
Jianping JI
;
Jianming PENG
;
Huizhong HUANG
- Publication Type:Journal Article
- Keywords:
Diabetes,type 2;
Insulin;
Rosiglitazone
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(6):955-957
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe rosiglitazone(RSG) combined with insulin therapy in type 2 diabetes pa-tients with tuberculosis. Methods 66 cases with type 2 diabetes and tuberculosis used the conventional antitubercu-losis treatment, divided into insulin group(DM + INS) 33 cases, the treatment group (DM + INS + RSG) 33 with dy-namic observation of blood glucose, and the lesions of tuberculosis in sputum culture. Results DM + INS + RSG group at the same time as the conversion rate is higher than DM + INS group(X2 = 8.45, X2 = 6.11,X2 = 12.87, P<0.05), the lesions were closed and empty absorption were significantly different (X2 = 15.60, P < 0.05 ; X2 = 5.00, P< 0.05), DM + INS group before and after treatment did not change significantly. After treatment DM + INS + RSGgroup FPG, PPG and HbAlc levels lower than before treatment(P < 0.05~0.01 ) and DM + INS group with sig-nificant differences( P < 0.05~0.01 ). Conclusion The addition of rosiglitazone to insulin treatment results in sig-nificantly improvement in glycemic control in the type 2 diabetic patients.