The detection of immune signs and their clinical significance in patients with JRA
- VernacularTitle:幼年类风湿关节炎免疫指标检测及临床意义
- Author:
Yazhen DI
- Publication Type:Journal Article
- Keywords:
Arthritis,juvenile rheumatoid;
Immunoaasay
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(6):974-975
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of detecting T cell subsets,immunoglobulin(Ig) ,erythro-cyte sedimentation rate(ESR),C-reactive protein(CRP) in patients with juvenile rheumatoid arthritis(JRA). Meth-ods T cell subsets(CD3+ , CD4+ , CD8+ , CD16+CD56+) was detected with flow cytometer, Ig, CRP with rate nephelome-try,ESR with Westergren's method in 40 cases of JRA,and other 40 normal children were served as normal control group. Results The level of CD3+ ,CD8+ ,CD16+CD56+ in the JRA group were lower,but CD4+ was higher than those in normal control group(P< 0.05 all) ;the level of IgA, IgG, IgM, ESR, CRP in the JRA group were all higher than those in the normal control group( P < 0.05 ). Conclusion There is an inflammation in patients with JRA, and when disease activity there is an immunological aberrance with cellular and humoral immunization.
