Human Immunodeficiency Virus Infection and Thrombotic Diseases
- VernacularTitle:人免疫缺陷病毒感染与血栓形成性疾病
- Author:
Yongmei YANG
;
Qinglong AI
- Publication Type:Journal Article
- Keywords:
human immunodeficiency virus;
acquired immunodeficiency syndrome;
thrombosis
- From:
International Journal of Cerebrovascular Diseases
2008;16(6):464-468
- CountryChina
- Language:Chinese
-
Abstract:
Anti-phospholipid antibody and lupus anticoagulant appear in the blood of patients with human immunodeficiency virus (HIV)infection,which result in the increased levels of von Willebrand factor and D-dimer,and decreased the levels of protein S,protein C,antithrombin and heparin cofactor,and thus rgsult in hypercoagulation status.In addition,the HIV infection itself and secondary opportunistic infections may also cause endothelial injury.Both hypercoag ulation status and endothelial injury may promote the occurrence of thrombotic diseases.
