Nuclear Factor-κB,Tumor Necrosis Factor-α and Cerebral Infarction
- VernacularTitle:核因子-κB、肿瘤坏死因子-α与脑梗死
- Author:
Jianbo XIE
;
Yufang CHEN
- Publication Type:Journal Article
- Keywords:
nuclear factor-κB;
tumor necrosis factor-α;
cerebral infarction
- From:
International Journal of Cerebrovascular Diseases
2008;16(6):469-472
- CountryChina
- Language:Chinese
-
Abstract:
Nuclear factor-κB(NF-κB),a transcription factor,which widely exists in neuron,neuroglial cell and vascular endothelial cell.It mainly participates in the inflammatory reaction,apoptosis,immunological reaction and other stress reaction of the body.It is considered as an initiation factot of vascular endothelial cell injury.Cytokines.such as tumor necrosis factor-α may promote the inflammatory cascade reaction in cerebral infarction,and may also play an important role in cerebral ischemic injury.
