Mechanisms of Hemorrhagic Transformation in Acute Cerebral Infarction
- VernacularTitle:急性脑梗死出血性转化机制
- Author:
Ke LI
;
Yumin LUO
;
Xunming JI
- Publication Type:Journal Article
- Keywords:
cerebral infarction;
hemorrhagic transformation
- From:
International Journal of Cerebrovascular Diseases
2008;16(6):456-459
- CountryChina
- Language:Chinese
-
Abstract:
With the wide development of intra-arterial thrombolysis,the risk factors and the occurrence mechanism of hemorrhagic transformation have drawn great attention.Hemorrhagic tramformation is the most dangerous complication of intra-arterial thrombolysis.The understanding of the occurrence mechanism of hemorrhagic transformation from macroscopic tO microscopic,it is attributed ultimately to the destruction of vascular wall structure or function.The related mechanisms include oxidative stress reaction,leukocyte infiltration and inflammatory reaction,vascular reaction,and extracellular proteolysis.
