Jianpi Qutan Decoction (Fortifing Spleen and Dispelling Phlegm Decoction) Combined with Quetiapine in Treating Negative Symptoms of Schizophrenia
- VernacularTitle:健脾祛痰汤合并喹硫平治疗精神分裂症阴性症状的临床观察
- Author:
Zhixia MAO
;
Genqi LI
;
Xinyu GUO
;
Yuan YANG
;
Juan CHENG
- Publication Type:Journal Article
- Keywords:
Jianpi Qutan Decoction;
Schizophrenia:Negative symptoms;
Quetiapine
- From:
International Journal of Traditional Chinese Medicine
2008;30(4):275-276
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy and side effects of Jianpi Qutan Decoction combined with Quetiapine in the treatment negative symptoms of schizophrenia.Methods 60 inpatients with schizophrenia were randomly divided into two groups,with one group treated with Jianpi Qutan Decoction combined Quetiapine and the other group treated with Quetiapine.Effects and side effects were assessed with the Positive and Negative Syndrome Scale (PANSS) and Treatment Emergent Symptoms Scale (TESS) respectively 1,4 and 8 weeks before and after the treatment.Results There was no significant difference in the overall efficacy between the two groups,but the improvement of the negative symptoms and illness provocation was significantly better in the treatment group than that in the control group respectively (P＜0.05).Moreover,the adverse reaction was milder in the treatment group.Conclusion It is suggested Jianpi Qutan Decoction in combination with typical antipsychotics is effective and safe in treating negative symptoms in schizophrenia patients.
