A clinical study of ropivacaine mesylate combined with nefopam hydrochloride in cesarean section postoperative patient-controlled epidural analgesia
- VernacularTitle:甲磺酸罗哌卡因复合盐酸奈福泮用于剖宫产术后硬膜外自控镇痛的临床研究
- Author:
Xiuying LI
;
Min TAO
;
Junxin YAN
;
Yawei ZHAO
- Publication Type:Journal Article
- Keywords:
Cesarean section;
Analgesia,epidural;
Ropivacaine mesylate;
Nefopam hydrochloride;
Tramadol
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(21):17-19
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effects of two patient-controlled epidural analgesia(PCEA) after cesarean section and the incidence of nausea vomiting, lethargy and urinary retention. Methods Sixty cesarean section patients were randomly divided into two groups, each group had 30 patients. Group Ⅰ: 0.15% bupivacaine hydrochloride plus tramadoL group Ⅱ: 0.179% ropivacaine mesylate plus nefopam hydrochloride. Postoperative 0-48 hours within the period pain (visual analog score, VAS)and the corresponding time motor block level(the Bromage scale), and incidence of nausea vomiting, lethargy and urinary retention were recorded. Results VAS difference was not statistically significant (P>0.05), Bromage scores in group Ⅱ was shorter than those in group Ⅰ(P<0.05), the incidence rates of nausea vomiting, lethargy and urinary retention in group Ⅱ were lower than those in group Ⅰ(P<0.01). Conclusion Ropivacaine mesylate combined with nefopam hydrochloride PCEA analgesic effect is certain, which shows a clear superiority in the motor function recovery and reducing the incidence of adverse reactions.
