The study of the relationship of the condition of inflammation and prethrombotic state in coronary heart disease complicated with essential hypertension and/or type 2 diabetes meilitus
- VernacularTitle:老年冠心病合并原发性高血压及2型糖尿病患者炎症与血栓前状态的相关研究
- Author:
Jing XIA
;
Jiehua LI
;
Haiqin TANG
- Publication Type:Journal Article
- Keywords:
Coronary artery disease;
Essential hypertension;
Type 2 diabetes mellitns;
C-reactive protein;
Prethrombotic state
- From:
Clinical Medicine of China
2008;24(8):765-767
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the condition of inflammation and prethrombotic state (PTS) of the aged patients with coronary heart disease(CHD) complicated with esstential hypertension(EH) and type 2 diabetes mellitns(T2DM). Methods The levds of fasting plasma hs-CRP,D-D and VWF were all measured in 86 CHD patients with EH,84 patients with T2DM,80 patients with EH and T2DM,91 CHD patients and 79 normal cases. Results Compared with normal group,diseases groups had significantly higher hs-CRP,D-D,and VWF,but compared with CHD with EH and T2DM group,other diseases groups had lower hs-CRP,D-D and VWF(P <0.05) ;The concentration of serum hs-CRP was positively correlated with D-D and VWF in CHD group (P < 0. 05). Conclusion The inflammation and hypercoagulable state is more significant in CHD patients with EH and T2DM,thns the levels of plasma hs-CRP,D-D and VWF play an important role in the treatment.
