Lipoprotein lipase activity anti its relationship to serum lipid levels in elderly
- VernacularTitle:老年人脂蛋白脂酶活性改变及其与血脂水平的关系
- Author:
Haixin ZHONG
;
Zhiqing HUANG
- Publication Type:Journal Article
- Keywords:
Elderly;
Lipoprotein lipase;
Triglyceride;
High density lipoprotein choleaterol
- From:
Clinical Medicine of China
2008;24(8):775-777
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate lipoprotein lipase (LPL) activity and its relationship to serum lipid. Methods Serum triglyceride (TG) ,total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and postheparin LPL activity in 40 elderly subjects and 45 subjects in control group. Results TG,TC and LDL-C levels were much higher in the elderly than in control group (P <0.05 orP <0.01) ;postheparin LPL activity was lower in elderly (P <0.05) ; and showed a negative correlation with serum TG level (r = -0. 513 ,P < 0.01), but was positively correlated with serum HDL-C concentration (r = 0. 390, P < 0.05). Conclusion The decreased activity of LPL in the elderly may contribute to hypertriglyceridemia associated with low level of high density lipoprotein cholesterol, and could be a risk factor for atherosclerosis.
