S-1 combined with cisplatin neoadjuvant chemotherapy in gastric carcinoma
- VernacularTitle:替吉奥联合顺铂新辅助化疗在胃癌中的应用
- Author:
Zhouchong WANG
- Publication Type:Journal Article
- Keywords:
Chemotherapy,adjuvant;
Stomach neoplasms;
Cisplatin;
S-1
- From:
Journal of International Oncology
2008;35(7):522-524
- CountryChina
- Language:Chinese
-
Abstract:
S-1 is a kind of fouth-generation oral fluoropyrimidine,including tegafur(FT),5-chloro-2,4-dihydroxypyridine(CDHP),and potassium oxonate(Oxo).S-1 is now used in 80% advanced gastric cancer patients in Japan,it's reported that CR+RR is over 44.6%.Neoadjuvant chemotherapy can reduce tumor loading,degrade the staging,afford operation possibility.S-1 combined with CDDP as a new neoadjuvant chemotherapy,is the most efficient therapy in advanced gastric cancer at present,it's CR can be over 76%.
