Application of oncolytic adenovirus in cancer gene therapy
- VernacularTitle:溶瘤腺病毒在肿瘤基因治疗中的应用
- Author:
Yi CHEN
- Publication Type:Journal Article
- Keywords:
Virotherapy,oncolytic;
Adenovirus E1A proteins;
Gene therapy
- From:
Journal of International Oncology
2008;35(7):483-485
- CountryChina
- Language:Chinese
-
Abstract:
Oncolytic adenovirus-mediated E1A gene therapy may be a useful therapeutic approach for cancer treatment.In addition to direct lysis,viruses also mediate exogenous tumor suppressor genes inducing antitumor efficacy.Vectors need further investigation to improve the targeting and effectiveness in vivo.
