Progress of correlative study between BRCA1 BRCA2,and breast cancer
- VernacularTitle:BRCA1和BRCA2基因与乳腺癌相关的研究进展
- Author:
Jie ZHOU
- Publication Type:Journal Article
- Keywords:
Genes,BRCA1;
Genes,BRCA2;
Mutation;
Breast neoplasms
- From:
Journal of International Oncology
2008;35(7):499-501
- CountryChina
- Language:Chinese
-
Abstract:
BRCA1 gene and BRCA2 gene are two anti-oncogenes which are correlative with the genesis and progress of breast cancer.especially hereditary breast cancer.Accumulative evidence shows there are BRCA1 and BRCA2 gene mutations in some patients with breast cancer and different clinico-pathological characteristics in BRCA1-and BRCA2-related breast cancer.Therefore,the detection of BRCA1 and BRCA2 gene mutation will be valuable for the prognosis of breast cancer.