Value of a novel rapid monoclonal enzyme immunoassay stool antigen and role of age in diagnosing Helicobacter pylori infection in children
- Author:
Josette Raymond
- Publication Type:Journal Article
- Keywords:
Monoclonal enzyme;
Immunoassay;
Antigen;
Children;
Infection;
Helicobacter pylori
- MeSH:
Helicobacter pylori;
Infection;
Child;
Antigens
- From:Journal of Preventive Medicine
2005;15(6):84-88
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
A novel rapid monoclonal enzyme immunoassay stool antigen for Helicobacter pylori (H. pylori) was evaluated among 115 children. The overall sensitivity, specificity, positive and negative predictive values were 86.2%, 92.9%, 78.1%, and 95.8%, respectively with an accuracy of 91.4%. The highest diagnostic value was observed in children above 10 years old with the sensitivity of 100% in comparison with a lower level of 75% in those below 5 years. All age groups exhibited a high negative predictive value that allows to exclude H. pylori infection in negative test cases. This helps avoiding unnecessary endoscopy- related stress to children.
