Application of p53 gene therapy for malignant lymphoma
- VernacularTitle:p53基因治疗在恶性淋巴瘤治疗中的应用
- Author:
Dongqing LI
- Publication Type:Journal Article
- Keywords:
Gene therapy;
Lymphoma;
Genes,p53
- From:
Journal of International Oncology
2008;35(7):547-549
- CountryChina
- Language:Chinese
-
Abstract:
In majority of malignant lymphoma patients the overexpression of mutant p53 gene can be found,and experiments show that p53 gene and the genesis currence and development of malignant lymphoma are closely related.Thus,normal p53 gene carried by recombinant adenovirus vector into tumor cells and its stable expression will play a theraputic role in the treatment of malignant lymphoma.This has been confirmed by the basic research.
