Clinical meanings of serum CA19-9 level in hepatocirrhosis patients
- VernacularTitle:肝硬化患者血清糖链抗原19-9的变化
- Author:
Xuezhen HUANG
;
Hong SUI
;
Juhui DENG
- Publication Type:Journal Article
- Keywords:
Liver cirrhosis;
CA- 19-9 antigen;
Chemiluminescence
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(7):1139-1140
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical meanings of serum CA19-9 levd in hepatocirrhosis patients. Methods 61 hepatitis B and hepatocirrhosis patients were as treatment group, and 35 normal were as control group. The content of serum CA19-9 was measured by dectrochemistry lighting and the liver function was determined too. According to Child-Pugh liver function integral method,the treatment group was divided into 27 cases of A grade,20 cases of B grade and 14 cases of C grade. Results The serum CA19-9 level in hepatocirrhosis patients was higher than that of normal group significantly(P< 0. 005 ). The serum CA19-9 level decreaed obviously through the treat- ment,thereinto A and B grade fell evidendy in the Child-Pugh liver function integral method( P < 0. 005). C grade was not significantly different(P<0.05 ). The serum CA19-9 levd was positivdy associated with TBiL, ALT and AST of liver function integral method. Conclusion The serum CA19-9 levd of hepatocirrhosis patients is improved in different degrees. And it can be a prognostic target and used to estimate the degree of damage of liver function of hepatocirrhosis patients.
