Study on multiple stem cell sources for mature vascular endothelial cells
- VernacularTitle:干细胞分化来源血管内皮细胞研究进展
- Author:
Wei FU
;
Wenjie ZHANG
- Publication Type:Journal Article
- Keywords:
Adult stem cell;
Embryonic stem cell;
Endothelial cell;
Differentiation
- From:
International Journal of Biomedical Engineering
2008;31(4):201-205
- CountryChina
- Language:Chinese
-
Abstract:
Stem cells offer considerable promise in the repair or replacement of damaged tissue in the body.Mature and functional endothelial cells play a pivotal role in neovascularization and maintenance of blood vessel integrity.Although being the best choice for transplantation endothelial,cells isolated from autologous vessels have been heavily obstacled in medical application due to poor resources and limitted proliferation potential in culture.Thus,stem cells have been the focus of the studies soareh for suitable cell sources.Several types of stem cells have been reported to possess endothelial cell differentiation potential.This article summarized the recent study on the sources,distribution,features-differentiation,animal experiments and clinical use of stem cells.Advantages and disadvantages are compared to provide a reference for the choice of evdothelial celia source.