Advance in the studies of xenogeneic/ ailogeneic bone materials
- VernacularTitle:异种、异体骨材料的研究进展
- Author:
Jingfeng LI
;
Qixin ZHENG
- Publication Type:Journal Article
- Keywords:
Immunogenicity;
Xenogeneic bone;
Scaffolds
- From:
International Journal of Biomedical Engineering
2008;31(4):249-253
- CountryChina
- Language:Chinese
-
Abstract:
Xenogeneic/Allogeneic bone materials are among the hot research interests of biological scaffolds.These materials are ideal materials for repairing bone defects because they have the structure and morphology of the natural bones,are able to be degraded and absorbed in the body,and are less immunogenic through appropriato treatment.Through further modification with biological molecules such as growth factors,they could provide a better microenvironment for the bone cells to grow into and fully differentiate.This article summarizes the factors affecting the immunogenicity of xenogeneic/allogeneic bone and the methods of removing immunogenicity.Advances in sintered bone materials,defatted bone materials,deproteinated bone materials,decalcifying bone materials,and composite materials are reviewed in greater details.
