Re-evaluating the relationship of serum CA125 value and prognosis in endometrial cancer
- VernacularTitle:子宫内膜癌患者血清CA125水平与预后关系的再评价
- Author:
Zhongmin WANG
;
Jiyong JIANG
- Publication Type:Journal Article
- Keywords:
Endometrial neoplasms;
Prognosis
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(21):20-22
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of various CA125 value in serum in instructing the treatment of endometrial cancer. Method The preoperative CA125 serum level of 147 cases of endometrisl cancer was examined by radioimmunoassay. Results Among patients with endometrial cancer, the CA125 level was higher in stages Ⅲ and Ⅳ than that in stages Ⅰ and Ⅱ (P<0.01). The sensitivity and specificity of CA125 > 20 kU/L in diagnosis of the endometrial cancer were 70.7% and 98.0%, and CA125 > 35 kU/L were 58.2% and 100.0%, respectively. The CA125 value of eases with cytological positive in abdomen was higher than that of cases with cytological negative. Conclusion The examination of CA125 serum level is valuable in the judgement of operative stages and lymph node metastasis in endometrial cancer.