Bilevel positive airway pressure ventilation in the patients with acute organophosphorus pesticides poisoning and respiratory failure
- VernacularTitle:双水平无创正压通气在急性有机磷农药中毒伴呼吸衰竭中的应用
- Author:
Jie SUN
;
Bin WU
;
Biao HANG
- Publication Type:Journal Article
- Keywords:
Acute organophosphoras pesticides poisoning;
Noninvasive positive pressure ventilation;
Respiratory failure
- From:
Clinical Medicine of China
2008;24(8):777-779
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of bilevel positive airway pressure mechanical ventilation (BiPAP) in the patients of acute organophosphorus pesticides poisoning (AOPP) with respiratory failure. Methods 44 AOPP patients with respiratort failure were randomly divided into experimental group (n = 22) and control group (n = 22). The routine trentment was given to both groups, additional BiPAP assisted ventilation was given to the treatment group. Blood gas,heart rate and respiratory rate were detected before and 2 h,24 h,48 h after treatment, and the rote of intubatinn,mortality,duration and cost of hospitalization were compared between two groups. Results Heart rate,PaO2 was significantly increased and PaCO2 decreased in BiPAP ventilation (P <0. 05). The mortality,intubatien rate and cost of hospitalization were significantly decreased in BiPAP treatment group (P < 0. 05). Conclusion The BiPAP ventilation is certainly effective to acute organophosphorus pesticides poisoning with respiratory failure. It could obviously improve the clinical symptoms and arterial blood gas analysis, and could reduce the mortaiity, rate of intubotion,cost of hospitalization of patients of acute organophosphoms pesticides poisoning with respiratory failure.
