Intrathoracic administration of Kushenhuangqi Injection combined with cisplatin in treatment of malignant pleural effusion
- VernacularTitle:苦参黄芪注射液联合顺铂胸腔内注射治疗肺癌胸水疗效观察
- Author:
Jiacai HU
;
Qingquan LI
;
Yishan XIE
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Phural effusion,malignant
- From:
Chinese Journal of General Practitioners
2008;7(8):561-563
- CountryChina
- Language:Chinese
-
Abstract:
Kushenhuangqi Injection is made from Chinese herb medicine flavescent sophora and astragalns roots.Seventy-one patients with malignant pleural effusion were randomly divided into two groups: 36 patients were treated with both intrathoracic Kushenhuangqi Injection and chemotherapeutic agent cisplatin (treatment group) and 35 patients were treated with cisplatin alone.The response rate of treatment group was significantly higher than that of control group (31/36 vs 20/35,u=3.020,P<0.01).The rate of adverse reaction (leucopenia,nausea,vomiting etc.) in treatment group was significantly lower that that of control group.The results indicate that Kushenhuangqi Injection can enhance the therapeutic effect of chemotherapeutic agent and reduce its adverse reaction in treatment 0f malignant pleural effusion caused by carcinoma of the lungs.
