Comprehensive treatment of liver cancer recurrence and metastasis after liver transplantation
- VernacularTitle:肝癌肝移植术后复发转移的综合治疗
- Author:
Fan HE
;
Zhishui CHEN
;
Fanjun ZENG
;
Dunfeng DU
;
Bin LIU
;
Min WU
;
Shengyuan XU
;
Xiaoping CHEN
- Publication Type:Journal Article
- Keywords:
Liver cancer;
Liver transplantation;
Recurrence;
Metastasis;
Comprehensive treatment
- From:
Chinese Journal of Digestive Surgery
2008;7(4):271-272
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of comprehensive treatment for liver cancer recurrence and metastasis after liver transplantation, and investigate the risk factors affecting the lifespan of patients with liver cancer recurrence and metastasis. Methods Of 29 patients with liver cancer recurrence and metastasis after liver transplantation, 11 patients in the comprehensive treatment group were treated by TACE, microwave coagulation, radiotherapy or hepatectomy, and the remaining 18 patients were classified into chemotherapy group. The differences in efficacy between the 2 treatment modalities were compared, and the factors influencing the patients' lifespan were analyzed. Results Compared with patients in the chemotherapy group, patients in the comprehensive treatment group had significantly longer lifespan after liver cancer recurrence and metastasis (t = 5. 617, P < 0.01). TNM staging, pathological classification, time of postoperative recurrence and metastasis and treatment method were the factors that influence the lifespan of patients with liver cancer recurrence and metastasis after liver transplantation (t =2.843, 3.061,22.781,5.617, P <0.01). Conclusions Comprehensive treatment could prolong the lifespan of patients with liver cancer recurrence and metastasis after liver transplantation. The efficacy of comprehensive treatment is superior to that of the chemotherapy.
