Use creatinine reduction ratio to predict the graft function recovery after kidney transplantation
- VernacularTitle:应用血肌酐下降率预测肾移植患者术后早期肾功能恢复情况
- Author:
Yun OUYANG
;
Bingyi SHI
;
Yeyong QIAN
;
Hongwei BAI
;
Jingyuan CHANG
;
Yuan DU
;
Yu FAN
;
Jingfeng JIA
;
Yawei WANG
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Delayed graft function;
Creatinine reduction ratio
- From:
Chinese Journal of Urology
2008;29(8):544-546
- CountryChina
- Language:Chinese
-
Abstract:
Objeetive To discuss the correlation of creatinine reduction ratio(CRR2)from posttransplant day 1 to day 2 and early graft function recovery status after kidney transplantation. Methods Clinical data of 80 patients after renal transplantation from Jan 2005 to Mar 2007 were retrospectively analyzed.Patients were divided into three groups according to the post-operative serum creatinine level:53 patients within IGF group[cereatinine＜265.2 μmol/L by post-operative day(POD)no.5],14 patients within SGF group(creatinine＞265.2 μmol/L on POD no.5,but no need for dialysis),and 13 patients within DGF group(need for dialysis in the first week post-transplant).Then the value and 99%CI of CRRz of these three groups were calculated. Results The value of CRR2 of IGF,SGF and DGF was(46.8±14.6)%,(25.6±13.5)%and(0.7±17.7)%respectively.And CRR2 99%CI of IGF,SGF and DGF was 41%-52%,15%-36%and-14%-16 0A respectively.There was significant difference in the value of CRR2 among IGF,SGF and DGF group.So a criteria for early diagnosis of IGF,SGF and DGF by CRR2 99%C1 was established:IGF(CRR2≥40%),SGF (15%＜CRR2＜40%)and DGF(CRR2≤15%). Conclusion CRR2 has a good correlation with early graft function recovery after kidney transplantation,and can be used to predict the occurrence of SGF and DGF.
