Relationship between serum prostate specific antigen and asymptomatic prostatic inflammation
- VernacularTitle:Ⅳ型前列腺炎与前列腺特异性抗原的关系
- Author:
Guizhong LI
;
Libo MAN
;
Guanglin HUANG
;
Jianwei WANG
;
Ning LIU
;
Feng HE
;
Hai WANG
;
Haidong WANG
;
Xinyu YANG
;
Tongli XIA
;
Yanqun NA
- Publication Type:Journal Article
- Keywords:
Prostatitis;
Prostate specific antigen
- From:
Chinese Journal of Urology
2008;29(8):520-523
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the relationship between asymptomatic prostatic inflammation (NIH category Ⅳ prostatitis)and serum prostate specific antigen. Methods In a retrospective study,245 prostate biopsies with benign pathological results from January 1998 to January 2000 were reviewed and the corresponding serum PSA before biopsy were analyzed.All patients were taken 6 or 13 cores prostate biopsy. Results One hundred and twenty-seven NIH-Ⅳ prostatitis and 118 patients with benign prostatic hyperplasia(BPH)were identified.The difference in free-PSA,totalPSA,f/t-PSA levels between BPH and NIH-Ⅳ prostatitis was significant(P＜0.05).In multivariate analysis,free-PSA,total-PSA,f/t-PSA was the significant predictors of histology in NIH-Ⅳ prostatitis(P＜0.05).The best prediction factors were constructed to predict pathology type in NIH-Ⅳ prostatitis:TPSA≥4 ng/ml,fPSA≥0.85 ng/ml and f/t-PSA≤0.16(P＜0.05). Conclusions Asymptomatic inflammation of the prostate was one of the confounding factors in patients with an elevated PSA.In the diagnosis of prostate diseases,it should be taken into account prostatitis might elevate the level of PSA.
