A Case of Behcet's Disease Associated with Protein S Deficiency.
- Author:
Jeong Soo SONG
1
;
Won PARK
Author Information
1. Department of Internal Medicine, College of Medicine, Inha University, Incheon, Korea.
- Publication Type:Case Report
- Keywords:
Behcet's disease;
Protein S deficiency
- MeSH:
Adult;
Dacarbazine;
Humans;
Male;
Plasma;
Protein C;
Protein S Deficiency*;
Protein S*;
Thromboembolism;
Ulcer;
Venous Thrombosis
- From:Korean Journal of Medicine
1998;55(3):427-431
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Protein S is a natural anticoagulant present in the plasma that serves as a cofactor for activated protein C. The protein S level is decreased in congenital deficiency, inflammatory syndrome, DIC, hepatic disorders, malignancy, and oral anticoagulant (warfarin) therapy. Protein S deficiency provokes recurrent thromboembolism, superficial and/or deep vein thrombosis. Behcet's disease is a multisystemic disorder presenting with recurrent oral and genital ulcerations as well as ocular involvement. The mechanism of vascular involvement of Behcet's disease is not fully understood. This is a case report of Behcet's disease associated with protein S deficiency in a 44 year old male patient with deep vein thrombosis. We report the case with relevant literature review.
