Advances of death-associated protein kinase in tumor
- VernacularTitle:DAPK在肿瘤中的研究进展
- Author:
Jun XIA
;
Qiru XIONG
- Publication Type:Journal Article
- Keywords:
death-associated protein kinase;
tumor;
methylation
- From:
International Journal of Surgery
2008;35(8):559-561
- CountryChina
- Language:Chinese
-
Abstract:
Death-associated protein kinase (DAPK) is a muhidomain calcium/calmodulin (CaM)-de- pendent Ser/Thr protein kinase with an important role in apoptosis regulation and tumor suppression. DAPK may serve as a diagnostic and prognostic tool to evaluate disease severity, progression, metastatic rate, and re- currence, and may serve as a target for therapeutic intervention.