Hepatic Cavernous Hemangiomas: Relationship between Speed of Intratumoral Enhancement during Dynamic MRI and Apparent Diffusion Coefficient on Diffusion-Weighted Imaging.
10.3348/kjr.2012.13.6.728
- Author:
Se Jin NAM
1
;
Kae Young PARK
;
Jeong Sik YU
;
Jae Joon CHUNG
;
Joo Hee KIM
;
Ki Whang KIM
Author Information
1. Department of Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul 135-720, Korea. yjsrad97@yuhs.ac
- Publication Type:Original Article
- Keywords:
Diffusion-weighted MR imaging;
Liver, MR;
Liver, neoplasms;
Hemangioma
- MeSH:
Adult;
Aged;
Contrast Media;
*Diffusion Magnetic Resonance Imaging;
Female;
Gadolinium DTPA/diagnostic use;
Hemangioma, Cavernous/*diagnosis;
Humans;
Image Enhancement;
Liver Neoplasms/*diagnosis;
*Magnetic Resonance Imaging;
Male;
Middle Aged
- From:Korean Journal of Radiology
2012;13(6):728-735
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To investigate the relationships between the apparent diffusion coefficients (ADCs) on diffusion-weighted imaging (DWI) and the speed of contrast-enhancement in hepatic hemangiomas. MATERIALS AND METHODS: Sixty-nine hepatic hemangiomas (> or = 1 cm) were evaluated with DWI, by using multiple b values (b = 50, 400, 800 s/mm2), followed by a gadolinium-enhanced dynamic MRI. The lesions were classified into three groups, according to the speed of contrast-enhancement on the portal phase. ADCs were measured on the ADC map automatically, and were calculated by using the two different b values (mADC50-400 with b values = 50 and 400; mADC400-800 with b values = 400 and 800 s/mm2). RESULTS: The mean ADCs (x 10-3 mm2/s) were significantly higher in the rapid group (1.9 +/- 0.44) than in the intermediate (1.7 +/- 0.35, p = 0.046) or the slow groups (1.4 +/- 0.34, p = 0.002). There were significant differences between the rapid and the slow groups in mADC50-400 (2.12 vs. 1.48; p = 0.008) and mADC400-800 (1.68 vs. 1.22, p = 0.010), and between the rapid and the intermediate groups in mADC50-400 (2.12 vs. 1.79, p = 0.049). Comparing mADC50-400 with mADC400-800, there was a significant difference only in the rapid group (p = 0.001). CONCLUSION: Higher ADCs of rapidly-enhancing hemangiomas may be related to richer intralesional vascular perfusion. Also, the restricted diffusion may be attributed to the difference of structural characteristics of hemangioma.
