Investigation of pathogen distribution and antibiotic resistance of ventilator associated pneumonia
- VernacularTitle:148例呼吸机相关性肺炎细菌分布特点及抗生素耐药性调查
- Author:
Di WU
;
Changshen YU
- Publication Type:Journal Article
- Keywords:
Ventilator associated pneumonia;
Bacteria drug-resistance
- From:
Clinical Medicine of China
2008;24(10):1033-1036
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the feature of pathogen distribution and antibiotic resistance of venti-lator associated pneumonia from Jan.to Dec,2007 in our ICU in order to provide a reference data guiding the appro-priate use of clinical antibiotics.Methods The 148 VAP cases of pathogen and drug sensitive tests were retrospec-tively analyzed.Results The incidence rate of VAP was 70.81%.Klebsiella pneumoniae,Pseudomonas aeruginosa,Escherichia coli,Acinetobacter sp were the top pathogen of Gram negative bacillus.Staphylococcus aureus (MBSA)was the major pathogen of Gram positive coccus.The resistance rates of Klebsiella pneumonia and Pseudomonas aeruginosa were very high.The effect rates of frequently used antibiotics were not satisfactory.The fungus infection rate was 6.76% among all the cases.Conclusion MRSA,Klebsiella pneumoniae and Pseudomonas aerugmosa are the major pathogens of VAP in our ICU with a high drug resistance rate.Gram negative bacillus is the major Pathogen of VAP with a faidy high drug resistance rate.
