Effect of Ondansetron on postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy with general anesthesia
- VernacularTitle:昂丹司琼对全麻腹腔镜胆囊切除术患者术后恶心呕吐的影响及护理
- Author:
Li LU
;
Meiling SUN
;
Xinqi WU
- Publication Type:Journal Article
- Keywords:
Ondansetron;
Postoperative nausea and vomiting;
Laparoscopic cholecystectomy
- From:
Chinese Journal of Practical Nursing
2008;24(24):23-24
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of Ondansetron on postoperative nausea and vomiting(PONV)in patient undergoing laparoscopic cholecystectomy with general anesthesia and the nursins care. Methods Ninety patients undergoing laparoscopic cholecystectomy with general anesthesia were randomly divided into 3 groups(n=30):low-dose Ondansetron group(O1 group)received 4 mg Ondansetron before section,high-dose Ondansetron group(O2 group)received 8 mg Ondansetron before section and the control group(C group)received normal saline.All injections were diluted to 4 ml.The number and degree of nausea and vomiting wag recorded during 24 h after operation.Results Number of patients with PONV in O1 group and O2 group were less than that of C group,P＜0.05,so was the PONV degree.No statistical difference was seen between O1 group and O2 group.Conclusion Intravenous injection of Ondansetron during operation can decrease the PONV in patient undergoing laparoscopic cholecystectomy with general anesthesia.
