Compensatory mechanisms of islet β cells In early stage of insulin resistance
- VernacularTitle:早期胰岛素抵抗胰岛β细胞代偿机制的研究进展
- Author:
Ying DAI
;
Wei CUI
;
Bingyin SHI
- Publication Type:Journal Article
- Keywords:
Islet B cell;
Compensation;
Glucose;
Free fatty acids
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(3):345-347
- CountryChina
- Language:Chinese
-
Abstract:
The response of normal islet β cells to insulin resistance is compensatory insulin hypersecretion in order to maintain normoglycemia. The mechanisms involved in the compensation process including the expansion of β cell mass and enhanced β cell performance via various molecular cascades, signaling pathway sand their interactions have been extensively investigated in recent years.
