Comparison of flurbiprofen axetil with tramadol for preemptive analgesia in patients undergoing laparoscopic hysterectomy
- VernacularTitle:氟比洛芬酯与曲马多对腹腔镜子宫切除术超前镇痛效果的比较
- Author:
Guangyi ZHAO
;
Lihong ZHANG
;
Lingxin MENG
- Publication Type:Journal Article
- Keywords:
Laparoscopy;
Hysterectomy;
Flurbiprofen axetil;
Tramadol;
Preemptive analgesia
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(18):12-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the preemptive analgesia effect of flurbiprofen axetil with tramadol in patients undergoing laparoscopic hysterectomy. Methods Ninety patients undergoing laparoscopic hysterectomy were divided randomly into group A (n=30), group B (n=30) and group C (n=30). The patients in group A were administrated 1mg/kg flurbiprofen axetil intravenously before tracheal intubation, and in group B 2mg/kg tramadol intravenously before tracheal intubation, while in group C 1mg/kg flurbiprofen axetil were administrated intravenously at the end of operation. The postoperative analgesic effects (1, 2, 4, 8, 12, 24 hours) were evaluated by VAS score and BCS score, while the times of pain-killer boosting and the side effects were recorded. Results VAS scores of group C were significantly higher than those of group A and B at all time points (P<0.05), except for 12 hours and 24 hours after the surgery, while BCS scores of group C Were lower than those of group A and B at the same time points (P<0.05).The side effects of group A and group C were significantly lower than those of group B (P<0.05). Conclusion Preemptive analgesia with flurbiprofen axetil and tramadol in patients undergoing laparoscopic hysterectomy is effective and convenient, while flurbiprofen axetil has less side effects.
