Effect of nasal midazolam on childhood febrile seizures
- VernacularTitle:咪达唑仑鼻腔给药治疗热性惊厥的临床研究
- Author:
Shaoyang OU
- Publication Type:Journal Article
- Keywords:
Midszolam;
Febrile seizures
- From:
Chinese Pediatric Emergency Medicine
2008;15(z1):28-29
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine which is more effective and safe treatment for controlling febrile seizures in children: Nasal midazolam or intravenous diazepam. Methods Thirty-six children, aged from 6 months to 6 years, with a diagnosis of febrile seizures and seen at Jieyang People's Hospital were in cluded inthis study. Midazolam 0.2～0.3 mg/kg was administered Nasally in 30 seconds by an injector, intravenous di-azepam 0.2～0.3 mg/kg was administered as control group. Results In the Nasal midazolam group, the seizures of 16(16/18) patients terminated in 10 minutes; In the intravenous diazepam group, 15(15/18) pa-tients terminated in 10 minutes, the difference was no statistically significant (P>0.05). the time from pa-tients arrival the hospital to the seizures terminated, the Nasal midazolam group is (209.2±26.1) s;the intra-venous diazepam group is (339.6±42.4) s, and the difference was statistically significant (P<0.05). Con-clusion Nasal midazolam is as effective as intravenous diazepam. However, It is easier to use in nasal drop. it will be very useful for febrile seizures.
