DNA methylation and gallbladder carcinoma
- VernacularTitle:DNA甲基化与胆囊癌
- Author:
Chunli WU
;
Xiaoping GENG
;
Lixin ZHU
- Publication Type:Journal Article
- Keywords:
DNA methylation;
gallbladder carcinoma;
genes;
neoplasms
- From:
International Journal of Surgery
2008;35(8):568-571
- CountryChina
- Language:Chinese
-
Abstract:
DNA methylation is a normal modification mode of eukaryon, there is an intimate relationship between aberrant promoter methylation of tumor-related genes and the generation or development of neo- plasms,emerging significantly biological effectiveness. Aberrant promoter methylation of tumor-related genes as the epigenetic markers, maybe play a very important role in the incidence, diagnosis, therapeutic effects, prognosis judgements and other aspects in gallbladder carcinoma.