Analysis of glucose dysbolism in patients with ectopic ACTH syndrome
- VernacularTitle:异位ACTH综合征患者糖代谢异常的特点分析
- Author:
Lei ZHAO
;
Yiming MU
;
Jingtao DOU
;
Juming LU
;
Changyu PAN
- Publication Type:Journal Article
- Keywords:
Cushing syndrome;
ACTH syndrome,ectopic;
Diabetes mellitus,secondary
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(4):410-411
- CountryChina
- Language:Chinese
-
Abstract:
The characteristics of glucose dysbolism in ectopic ACTH syndrome (EAS) were investigated by analysing the clinical data of 117 patients with Cushing syndrome (CS). The patients with CS were divided into 3 groups : EAS group (n = 9) , Cushing's disease (CD) group (n = 67) and adrenocortical adenoma (AA) group (n =41). Retrospective analysis of the data covered the prevalence of secondary diabetes, blood glucose, HbAlc, blood potassium, and blood ACTH and 24 h urinary-free cortisol (UFC) levels. Compared with CD and AA groups, the prevalence of secondary diabetes and blood glucose level were higher in EAS group, while HbAlc level was lower. Blood glucose level in patients with ectopic ACTH syndrome decreased to normal after tumor removal.
