Effects of C-peptide on development of chronic diabetic complications and its mechanism
- VernacularTitle:C肽在糖尿病慢性并发症发生和发展中的作用及其机制
- Author:
Jian WANG
;
Hong CHEN
- Publication Type:Journal Article
- Keywords:
C-peptide;
C-peptide receptor;
Diabetic chronic complications
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(4):463-464
- CountryChina
- Language:Chinese
-
Abstract:
Recent studies have suggested that C-peptide in the nanomolar concentration range binds specifically to cell surfaces and plays an important role in the pathological mechanism of chronic complications of diabetes mellitus, via improving the microcirculation, diminishing glomerular hyperfiltration, reducing urinary albumin excretion, protecting the cardiac function and preventing nerve dysfunction. The effects of C-peptide on the development of the chromic diabetic complications and its mechanisms are reviewed.
