Anti-sex hormone-dependent neoplasm agents-induced bone loss
- VernacularTitle:抗性激素依赖性肿瘤药物引起的骨丢失
- Author:
Eryuan LIAO
- Publication Type:Journal Article
- Keywords:
Sex hormone-dependent neoplasms;
Chemotherapy;
Bone loss;
Osteoporosis
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(4):351-353
- CountryChina
- Language:Chinese
-
Abstract:
Chemotherapy can induce bone loss. It is especially severe and the incidence of estimated bone loss may be as high as almost 100% for cancer patients treated with anti-sex hormone agents because of inhibition and deficiency of estrogens and/or androgens with the inappropriate ratio of two hormones during and "after therapy. Anti-sex hormone-dependent neoplasm agents-induced bone loss, characterized by an increase of bone turnover rate, should be treated in the early stage in order to prevent it from deterioration and bone fractures. The etiology, mechanism and clinical management of anti-sex hormone-dependent neoplasm agents-induced bone loss are briefly discussed in this review.
