Clinical analysis of 7 patients with Paget's disease of bone
- VernacularTitle:Paget'z骨病(畸形性骨炎)七例临床分析
- Author:
Xianling WANG
;
Guang YANG
;
Juming LU
;
Jingtao DOU
;
Yiming MU
;
Junhua MENG
;
Changyu PAN
;
Huaiyin SHI
- Publication Type:Journal Article
- Keywords:
Osteitis deformans;
Bisphosphonates;
Diagnosis;
Paget's disease of bone
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(4):412-414
- CountryChina
- Language:Chinese
-
Abstract:
Clinical and imageological characteristics of Paget's disease of bone in 7 patients who were treated in our hospital from 1991 to 2007 were analyzed. The data showed (1) 6 patients had the symptoms of bone pain and bone deformity, with more long bones involved; (2) Serum alkaline phosphatase was over normal range; (3) Imageology showed that osteoclasia was usually combined with bone sclerosis; (4) All the patients were treated with bisphosphonates; (5) 2 patients with serious bone deformity were treated with orthomorphia. Paget's disease of bone is a kind of metabolic bone disease with the characteristics of osteoclasia combined with bone sclerosis. The main features are bone pain and bone abnormality. Bisphosphonates are the first choice of drugs. Patients with serious bone deformity should be treated with orthomorphia.
