Two Cases of Systemic Amyloidosis Presenting with Abnormalities in Liver Function Tests.
- Author:
Jin Hyung PARK
1
;
Chang Kun PARK
;
Young Mi YUN
;
Dong Woo HYUN
;
Eun Soo KIM
;
Soo Young PARK
;
Chang Min JO
;
Won Young TAK
;
Young Oh KWEON
;
Sung Kook KIM
;
Yong Whan CHOI
Author Information
1. Department of Internal Medicine, Kyungpook National University College of Medicine, Daegu, Korea. yokweon@knu.ac.kr
- Publication Type:Case Report ; English Abstract
- Keywords:
Amyloidosis;
Liver function tests;
Hepatomegaly
- MeSH:
Adult;
Amyloidosis/complications/*pathology;
Female;
Hepatomegaly/complications/*diagnosis/pathology;
Humans;
*Liver Function Tests;
Male;
Middle Aged
- From:The Korean Journal of Gastroenterology
2003;42(4):341-346
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic amyloidosis results from the deposition of insoluble, fibrous amyloid proteins. It occurs mainly in the extracellular spaces of multiple organs and tissues including the kidney, heart, and liver. Although amyloid deposition in the liver is common in patients with systemic amyloidosis, clinically apparent liver disease is relatively rare. Indeed, most patients with systemic amyloidosis manifest only minimal to moderate hepatomegaly and trivial abnormalities in liver function tests. Recently, we experienced two cases of patients who presented with abnormalities in liver function tests and hepatomegaly as manifestations of systemic amyloidosis. We report these cases with a review of the relevant literatures.
