Sj(o)gren's syndrome and esophageal motility disorders
- VernacularTitle:干燥综合征与食管功能障碍
- Author:
Haiyun LI
;
Yi ZHENG
;
Zhanmin SHANG
;
Xin DONG
;
Yuewu LU
;
Yongfeng ZHANG
;
Xi CHEN
;
Xuhua SHI
- Publication Type:Journal Article
- Keywords:
Sj(o)gren's syndrome;
Esophageal motility disorders
- From:
Chinese Journal of Rheumatology
2008;12(9):619-621
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the manifestations of esophageal motility disorders and evaluate the association between them and dysphagia, laboratory tests and other accessory examinations in patients with Sj(o)gren's syndrome (SS). Methods Esophageal manometry was performed in 31 patients with SS and 18 healthy volunteers by the step pull-through method. Results Decreased upper esophageal sphincter pressure was detected in 19 of the 31 patients (61%) with SS, while 4 of 18 (22%) in controls. The frequency was significantly higher in patients than in healthy controls (P=0.008). Fifteen of 31 patients (48%) showed various patterns of esophageal dysfunction including ineffective esophageal motility in 6 patients, nutcracker esophagus in 3 patients and nonspecific dysmotility in 6 patients. No major differences were found in esophageal parameters (peak amplitude, wave duration and velocity) when comparing primary SS with secondary SS. These esophageal abnormalities were not correlated with clinical manifestations, laboratory examinations and other auxiliary examinations. Conclusion Patients with SS may have esophageal motility disorders, which can presents with different patterns.
