Clinical analysis of pulmonary arterial hypertention in systemic lupus erythamatosus
- VernacularTitle:系统性红斑狼疮肺动脉高压63例临床分析
- Author:
Liqing ZHANG
;
Mengtao LI
;
Xiaofeng ZENG
;
Dongyun YAO
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus,systemic;
Hypertention,pulmonary;
Lupus nephritis
- From:
Chinese Journal of Rheumatology
2008;12(9):626-628
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinic manifest-rations, mechanism, diagnosis and treatment of pulmonary arterial hypertention (PAH) in systemic lupus erythamatosus (SLE). Methods The clinic symptoms, laboratory tests. Doppler tests of patients who were diagnosed with PAH and SLE during last five years were analyze retrospectively. Results Anti-RNP antibody's prevalence rate was high. The presence of pulmonary arterial perssure (PAP) was not related to SLE disease active index (SLEDAI). Those who had PAP higher than 45 mm Hg were prone to have Raynaud's phenomenon PAH had no association to auto-antibodies and other systemic lesions. There were no differences in clinic features, auto-antibodies and other examinations between those with kidney injure and without kidney injure. Conclusion PAH may develop insidiously in SLE, so early diagnosis and prompt treatment of PAH can improve the prognosis.
