Gene Polymorphisms Associated with Vascular Function and Cerebrovascular Disease
- VernacularTitle:与血管功能有关的基因多态性与脑血管病
- Author:
Weiwei LI
;
Zhenzhong LI
- Publication Type:Journal Article
- Keywords:
cerebrovascular disease;
gene polymorphism
- From:
International Journal of Cerebrovascular Diseases
2008;16(8):608-614
- CountryChina
- Language:Chinese
-
Abstract:
Cerebrovascular disease is caused by the interaction of both environmental and hereditary factors.Among them,the hereditary factors mainly influerre the occrrence of cerebrovascular disease through gene polymorphisms.This article mainly reviews gene polymorphisms that influence vascular function,including ACEI,Col3A1,Col4AI,KRIT1,PDCD10,Notch3 and ANP.Meanwhile,the literatures were classified and discussed according to the standard of criterion of the evidence grades in medical literatures.Present research situation of the relation between various gene polymorphisms and cerebrovascular diseases is summarized and overviewed.
