Mechanisms of Stroke-Induced Peripheral Immunodepression
- VernacularTitle:卒中诱导外周免疫抑制的机制
- Author:
Jingcui QIN
;
Zhijun ZHANG
- Publication Type:Journal Article
- Keywords:
stroke;
immunodepression;
mechanism
- From:
International Journal of Cerebrovascular Diseases
2008;16(8):620-624
- CountryChina
- Language:Chinese
-
Abstract:
The nervous system and the immune system maintain homeostasis mainly through the hypothalamo-pituitary-adrenal(HPA)axis,the sympathetic nervous system and the parasympathetic nervous system(vagal cholinergic pahway).The homeostasis is broken after stroke,and results in peripheral immunosuppression,which is called stroke-induced immunodepression syndrome.Its mechanism is still under investigation.The article reviews the mechanism and clinical significance of stroke-induced peripheral immunodepression through the above three mentioned pathways.