Serum levels of soluble B7-H3 in patients with bacteremia and chronic hepatitis B and its clinical significance
- VernacularTitle:可溶性B7-H3在菌血症及慢性乙型肝炎患者体内的水平及临床意义
- Author:
Jing CHENG
;
Guohao GU
;
Guangbo ZHANG
;
Weili ZHANG
- Publication Type:Journal Article
- Keywords:
Bacteremia;
Chronic hepatitis B;
Soluble
- From:
Chinese Journal of Clinical Infectious Diseases
2008;1(3):145-148
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the seruln levels of solubl B7-H3(sB7-H3)in patients withbacteremia and in those with chronic hepatitis B(CHB),and its clinical significance.Methods Serumlevels of sB7-H3 from 50 bacteremia patients,78 CHB patients and 50 healthy individuals wero detected byEUSA,and its correlations with the quantities of leucocytes,neutrophils,lymphocytes and monocytes wereanalyzed.Results The average level of sB7-H3 in serum of bacteremia patients was(50.69±26.43)μg/ml which was higher than that of healthy group(P＜0.01);serum sB7-H3 level of patients with CHB was(18.07±7.28)μg/ml,and it had no significant difference compared with that in the healthy group(P＞0.05).Besides,positive correlations between the scrum sB7-H3 level in and the quantities of leucocytesand granulocytes were observed in bacteremia patients.Conclusions It suggests that sB7-H3 misht bepotentially used as a new parameter to improve the clinical diagnosis of bacteremia.
