Endoscopic Resection of Early Gastric Cancer.
10.5124/jkma.2010.53.4.299
- Author:
Kwi Sook CHOI
1
;
Hwoon Young JUNG
Author Information
1. Department of Internal Medicine, University of Ulsan College of Medicine, Korea. hyjung@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Early gastric cancer;
Endoscopic mucosal resection;
Endoscopic submucosal dissection
- MeSH:
Japan;
Lymph Nodes;
Neoplasm Metastasis;
Stomach Neoplasms;
Ulcer
- From:Journal of the Korean Medical Association
2010;53(4):299-305
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Endoscopic mucosal resection (EMR) has been accepted as one of the standard treatments of early gastric cancer (EGC) with a negligible risk of lymph node metastasis. EMR is similar to surgery in efficacy but less invasive and more cost-effective. And it allows accurate histological staging of the tumor, which is critical in deciding whether additional treatment is necessary. Standard indications for EMR of EGC include differentiated elevated cancer less than 2 cm in size and depressed cancer without ulceration less than 1 cm in size. Recently, expanded indication has been proposed in Japan to cover other lesions with a negligible risk of lymph node metastasis, which include larger lesions and lesions with ulceration. With the development of endoscopic submucosal dissection (ESD), en bloc resection of larger and even ulcerative lesion is possible. However, the lack of long-term data makes it difficult to widely accept expanded indication. More long-term studies about therapeutic outcomes are needed to fully bolster the safety and establish correct therapeutic role of ESD in treatment of EGC.
